Platelet-rich plasma (PRP) therapy is a form of regenerative medicine, consisting of injection of patient's blood plasma enriched with platelets, or thrombocytes. Platelet aggregation plays an important role in natural immune system defense, as platelets release a large number of growth factors stimulating immune system. The platelets are prepared from the whole blood centrifugated at low speed in order to separate plasma from the blood cells. The fraction of platelets is usually enriched with leucocytes (white blood cells) for additional effect. Typically, the injections are made into joints, ligaments and muscles. Growth factors released by platelets induce autologous adult stem cells and help to regenerate the damaged tissues. Microinjections of PRP in face and skin induce skin regeneration and rejuvenation.

Benefits:

• Restoration of damaged joints, ligaments and muscles
  
• Regeneration of cartilage tissue
  
• Reduction of chronic pain in joints and muscles
  
• Skin tissues rejuvenation
  

There are many kinds of stem cells, with different potency of development into different mature cell types and different profiles of treated diseases and side effects. One of the safest and most efficient types of stem cells is called autologous mesenchymal cells.

Autologous means that these cells derive from the patient's own body, usually adipose tissue or bone marrow. Therefore, these autologous stem cells do not cause autoimmune reaction and can easily grow in the body after terminal differentiation.

Mesenchymal means that these cells derive from mesenchyme, embryonic connective tissue. As such, mesenchymal stem cells (MSCs) are multipotent, i.e. they have potential to differentiate into many types of mature adult cells in multiple organs and tissues. MSCs can replicate as undifferentiated cells for a long time and potentially develop into many cell types of mesenchymal lineage, such as bone, cartilage, adipose, neural and hematopoietic cells. MSCs are found in many organs and tissues, such as adult marrow, adipose tissue and intestinal layers.

Multipotency, safety and lack of autoimmune reaction make autonomous MSCs one of most efficient and popular tools in cell therapy. Importantly, they are relatively easy to extract from adipose tissue or bone marrow. With modern lab methods, the whole process of extraction, preparation and administration takes about 4 hours for most indications.

Examples of diseases and conditions treated with MSCs

• Alopecia
  
• Congestive heart failure (CHF)
  
• COPD
  
• Diabetes Miellitus
  
• Erectile disfunction
  
• Macular degeneration
  
• Multiple sclerosis
  
• Orthopedic arthritis and injuries
  
• Rheumatoid arthritis (RA)
  
• Spinal cord injuries
  
• Systemic lupus erythematosus (SLE)
  

At Santa Maria, we use autologous mesenchymal cells for the following conditions:

• Face rejuvenation
  
• Hair loss
  
• Joints pain and diseases (osteo arthritis)
  

The therapeutic mud from the Sea of Cortez has a powerful anti-infective effect, both against bacteria and fungal infections. This therapeutic mud contains hundreds of biologically active components, some of which are natural antibiotics. It is important to note that, with a high degree of probability, these antibiotics are new, making them effective against antibiotic-resistant bacteria. Nowadays, most bacterial strains present on our skin are resistant to the wide variety of antibiotics available on the market. However, these strains are susceptible to the action of our therapeutic mud. According to dermatologists who use our mud in clinics, just 2-3 sessions of peloid therapy for the facial area are enough to completely eliminate acne. Additionally, the mud is effective in treating psoriasis and other skin conditions.

Moisturizing and nourishing masks for the skin of the face, neck, and décolleté. They can be used both after various cosmetic procedures to enhance the effect and on their own.

Facial ultrasound cavitation is a natural rejuvenation procedure that helps tighten all tissues without surgical intervention. This modern method restores tone, lifts, and even repositions facial muscles, fascia, and fat pads. As a result, the face gains a natural, youthful appearance without surgery, and the effect lasts for a long time. Special attachments are used for the face and neck.

A procedure involving targeted subcutaneous injections of hyaluronic acid-based products. It helps to hydrate and improve the appearance of the skin, slows down aging, and smooths wrinkles. On average, the effect lasts for 6–12 months. To achieve a long-lasting result, multiple sessions are recommended. The number of sessions depends on the goals of biorevitalization.

Mesotherapy is an intradermal injection of cocktails containing hyaluronic acid, vitamins, trace elements, amino acids, oligo-elements, lipolytics, and peptides.

Facial peeling is the removal of dead skin cells. It helps reduce pigmentation, minimize wrinkles, eliminate post-acne marks, and improve skin tone.
The result of the procedure is a refreshed, attractive, and healthy-looking complexion.

HydraFacial is a patented method for treating, rejuvenating, hydrating, and cleansing the skin in a single procedure. The HydraFacial^® technology offers a comprehensive approach to skin health by combining five full treatments in one: microdermabrasion, chemical peeling, deep cleansing and treatment, intensive hydration and antioxidant therapy, and lymphatic drainage massage.

Many women carefully monitor their appearance and actively take care of their facial skin. However, there may come a time when skincare products are no longer sufficient, and it becomes necessary to look for effective solutions to combat signs of aging. That’s when facial rejuvenation devices come to the rescue.
Such a device can be considered a full-fledged alternative to surgical intervention, as it allows for addressing a wide range of age-related skin concerns on both the face and body. The device comes with multiple interchangeable cartridges, enabling the selection of different penetration depths (ranging from 1.5 to 13 mm).
Thanks to the microcurrent stimulation from low-power electric charges, fine wrinkles are smoothed out, the skin gains tone, blood circulation improves, cells receive more oxygen, and the natural production of collagen is activated.

Indications:

• Post-acne
• Inflammatory skin conditions
• Dull skin tone
• Skin laxity, fine wrinkles
• Pigmentation spots

Effects:

• Improvement of tissue blood supply
• Increase in skin turgor through stimulation of natural collagen production
• Anti-aging effects (wrinkle reduction, elimination of pigmentation spots, improvement of skin tone)
• Anti-inflammatory effect
• Reduction of scars, including post-acne scars

Cryolipolysis is an innovative technique that targets subcutaneous fat tissue, promoting fat layer reduction and body contouring. It is the most powerful non-surgical procedure for fat reduction.
The effect is based on controlled, non-invasive local cooling of fat tissue. Prolonged cooling of fat cells (for about one hour) causes their destruction, while cold exposure does not damage the surrounding tissues. This is due to the selective sensitivity of adipocytes (fat cells) to cold, known as the paradox of white adipose tissue. The fat cells die naturally through the process of apoptosis. This type of cell death is considered safe for the body since it does not trigger a significant inflammatory response or release of fat breakdown products into the lymphatic and circulatory systems.
Cryolipolysis is considered a non-surgical alternative to liposuction. The procedure allows for the reduction of the fat fold volume, which is measured beforehand using a special instrument, by up to 40%.
To ensure effective cooling of subcutaneous fat without causing frostbite on the skin surface, specialized vacuum applicators are used in the devices. During the procedure, the vacuum draws the fat fold into the inner chamber of the applicator and holds it in place. This process separates the fat fold from the underlying muscles and organs, reducing the cold’s impact on them. Heat is removed from both sides of the fold simultaneously, while the vacuum compresses the subcutaneous fat and temporarily reduces blood circulation in the area, further enhancing the effectiveness of cryolipolysis.
The treatment area can be anywhere—cryolipolysis is performed on the arms, back, thighs, abdomen, and buttocks.
A cryolipolysis session lasts between 30 to 60 minutes and is generally comfortable for the patient. The equipment is safe and will automatically shut off in case of improper skin capture by the applicator, critical temperature deviations, or other malfunctions. During the procedure, the treated area undergoes massaging effects—pressure inside the applicator chamber changes periodically. Initially, the patient may feel cold and slight discomfort from the suction, but within 10 minutes, this sensation subsides, and numbness sets in. Patients can engage in other activities during the session—reading a book, a magazine, or using a laptop will not interfere.
After a one-hour treatment, the skin may appear red, but this typically fades within a few hours. The final result of the procedure develops within 1.5 to 2 months, with a single session leading to a 20%-40% reduction in the fat fold.
If the patient is not satisfied with the results of a single procedure, the application can be repeated in the same area with a 6-week interval. Typically, multiple cryolipolysis sessions are performed on different areas to achieve the ideal body contours. The number of areas treated in one visit is not limited.

The device promotes subcutaneous collagen proliferation, stimulates the replacement of lost proteins, enhances skin firmness, and restores skin elasticity.
This is a high-intensity ultrasound technique. Its principle is based on two ultrasound beams meeting beneath the skin at a predetermined depth, creating a cavitation effect. From physics, we remember that cavitation is a hydraulic shock that causes boiling due to the rapid movement of water molecules under ultrasound exposure, forming microscopic vapor bubbles. This effect leads to thermal stimulation of collagen, an immediate skin-tightening effect, and fat destruction.

The procedure is recommended if you have:

• Fat folds and deposits on the abdomen, back, buttocks, sides, and thighs;
• Cellulite (of any severity)
• Post-liposuction or lipolytic injection effects (remaining fat accumulations in the form of lumps)

Advantages of the procedure:

• No age restrictions
• Even body contouring
• No need for anesthesia (not even local) or painkillers
• Can be applied to a large body area
• No rehabilitation required
• Skin integrity remains intact (no punctures or incisions)
• No scars, noticeable swelling, or hematomas after the session
• Skin sensitivity is fully preserved
• Lifting effect (skin tightening)
• Results are visible after several sessions
• Cumulative effect
• Significant body contouring improvement after completing the course
• No strict restrictions, even on the day of the procedure

About the Procedure

EM Slim NEO is a device for muscle training using an electric field and non-invasive fat burning. It generates a pulsating low-frequency electromagnetic field capable of penetrating up to 8 cm deep into the body. The field configuration is designed so that the induced electric field activates muscle fibers throughout the entire depth of exposure. As a result, the muscles contract continuously during the procedure. Unlike regular workouts, all muscles in the path of the electromagnetic waves are engaged. When applied to the abdominal area, a 30-minute EM Slim session is equivalent to 20,000 crunches, which is unattainable during conventional gym workouts. The procedure is completely painless. After the session, mild muscle soreness, similar to that experienced after an intense workout, may occur.

Advantages

• Muscle growth up to 18%
• Elimination of excess fat
• Lymphatic drainage effect