Stem Cell Therapy
that prepares first,
then delivers.
At Santa Maria, we require a mandatory pre-conditioning protocol before any stem cell infusion. Most clinics skip it. We built our entire protocol around it.
What Makes Santa Maria Distinct
Santa Maria Health sits on the Pacific coast of Baja California, set within oceanfront community — built as an integrative medicine retreat rather than a conventional medical facility. The environment is part of the therapy.
What makes Santa Maria distinct is not any single element in isolation. It is the combination of four things under one roof.
Scientific Foundation
Research-trained leadership with a PhD in molecular genetics and 100+ peer-reviewed publications
Pre-Conditioning Protocol
Grounded in the biology of how stem cells actually work — a prepared environment before delivery
Per-Batch Quality Control
Strict screening including the 61-gene oncogenicity panel not standard at other clinics
Integrative Environment
Cell therapy as part of a complete healing process, not a standalone injection
What Are Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are adult cells derived from donor tissue — not embryonic. MSCs reduce systemic inflammation, repair damaged tissues, and modulate the immune system. They are used in hundreds of clinical studies worldwide.
At Santa Maria, we use allogeneic (donor-derived) MSCs from multiple tissue sources. The medical team selects the appropriate cell type based on each patient’s condition.
| Umbilical cord | Rheumatoid arthritis, autoimmune conditions, joint and connective tissue disorders. High potency, strong immunomodulatory profile. |
| Placenta | Autoimmune conditions. Similar profile to umbilical cord MSC. |
| Dental pulp | Neurodegenerative conditions, neurological support. Preferred for central nervous system applications. |
| Adipose tissue | Anti-aging, general rejuvenation, systemic support. |
- Specialized Dendritic cell preparations — targeted immune applications, including the Lyme disease protocol
- Specialized Activated lymphocyte preparations (CD4/CD8) — intravenous immune support
- Adjunct Exosomes — cell-free regenerative signaling, used as adjunct therapy
Why Pre-Conditioning Matters
Most clinics inject cells on day one. We don’t.
Stem cells do not function as free-floating cells. They require a biological niche supported by the lymphatic system and tissue microenvironment.
When the lymphatic system is congested or the tissue environment is inflamed, transplanted cells cannot survive and act effectively. We prepare this niche first — then deliver the cells.
This is a core reason the Santa Maria protocol is longer than same-day IV clinics — and why outcomes depend on the preparation phase as much as on the cells themselves.
Lymphatic Drainage
Clearing the lymphatic system to prepare the cellular environment for engraftment
Blood Microscopy
Live blood analysis to assess baseline cellular and immune status
Comprehensive Baseline Diagnostics
Full panel to individualize the protocol to each patient’s specific biology
IV Nutrient Loading
Targeted intravenous nutrients to support cellular reception and tissue receptivity
Inflammation Reduction
Targeted interventions to reduce systemic inflammation before cell delivery
Quality Control & Batch Screening
Every batch undergoes genetic screening via a 61-gene oncogenicity panel — a test that screens for mutations in cancer-associated genes. This level of screening is not standard practice across clinics.
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61-gene oncogenicity panel
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Full viral panel: Hepatitis B, C, HIV, CMV, HSV, EBV, respiratory pathogens
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Bacterial sterility testing (Gram stain + culture)
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Endotoxin testing
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Mycoplasma screening
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Chagas disease
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Immunophenotyping per ISCT international standard
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Batch-specific Certificate of Analysis available on request
Studies. Zero tumor formation.
A 2023 systematic review of 217 studies confirmed that mesenchymal stem cells do not form tumors across reviewed clinical and preclinical data.
The laboratory supplying our cells operates under COFEPRIS authorization with ISO-classified cleanroom facilities (cascading ISO 5–8), GMP-aligned manufacturing, and FACT certification in progress.
Request Certificate of AnalysisConditions We Treat with Stem Cell Therapy
Every case is individually assessed by the medical team. Candidacy is determined after a free medical consultation.
Autoimmune Conditions
Rheumatoid arthritis, multiple sclerosis, lupus, psoriasis, and systemic inflammatory diseases
Neurological Conditions
Parkinson’s disease, neuropathy, post-stroke recovery, traumatic brain injury
Joint & Tissue Conditions
Osteoarthritis, degenerative disc disease, sports injuries, tendon and ligament damage
Cellular Rejuvenation
Systemic inflammation reduction, energy restoration, immune optimization, biological age improvement
Chronic & Metabolic Conditions
COPD, diabetes (Type 1 and 2), kidney disease, liver conditions, erectile dysfunction
Lyme Disease — Dedicated Protocol
Santa Maria offers a dedicated protocol distinct from standard MSC therapy, built around an immunological approach — including dendritic cell preparations — tailored to each patient. Details are discussed during clinical consultation.
Every case is evaluated individually. Candidacy is confirmed after consultation.
Free ConsultationScientific Foundation
Santa Maria’s approach is anchored by the credentials of the clinic’s scientific leadership. The co-founder and scientific director brings decades of academic and clinical research to every protocol decision.
Individual results vary — the medical team discusses realistic expectations during consultation. Biomarker data from certain protocols show measurable improvements in biological age indicators.
- Professor of Medicine, University of Sharjah (UAE)
- PhD in Molecular Genetics
- 20+ years as academic scientist and biotech executive
- Author of 100+ peer-reviewed publications
- Two books on systems biology
- Research background in immunosequencing and immune system function
Patients treated over seven years of clinical operation
Years of clinical operation on the Pacific coast of Baja California
Peer-reviewed publications by the clinic’s scientific director
Languages on-site: English, Russian, Spanish. International patients welcome.
Stem Cell Therapy in Mexico —
Legal and Regulated
Regulatory Framework
Stem cell therapy using expanded MSCs is legal and regulated in Mexico under COFEPRIS oversight — the functional equivalent of the FDA.
Mexico is one of several jurisdictions that permit off-label and compassionate-use stem cell therapy under regulatory supervision.
The 2021–2022 FDA restriction on off-label stem cell use is a regulatory decision specific to the US framework — not a reflection on safety or efficacy.
Getting Here
Santa Maria sits on the US-Mexico border corridor — the most accessible medical tourism destination in the Americas.
Frequently Asked Questions
Begin with a Free Medical Consultation
Every patient starts with a no-obligation consultation. Our medical team reviews your case, answers your questions, and determines whether you’re a candidate.
Rosarito, Baja California, Mexico · info@stmariahealth.com · +1 858-209-6855